Type II Variation Submission Plan 53
This submission plan coordinates owners, milestone dependencies, and readiness controls for Upadvex. Teams use it to monitor timeline health, resolve blockers, and decide whether content is publish-ready for sequence assembly. Readiness is calculated from deterministic component approval status across linked dossiers, rather than manual estimates. Use the edit and content assembly actions to move directly into corrective work.
Plan ID
PLAN-053
Application
Target Date
2025-11-09
Status
In Progress
Owner
James O'Brien
Created
2022-03-25
Readiness Score
10/100
Calculated from 2 approved of 20 linked content components.
Blockers
8 components are missing approval snapshots.
9 components still have unresolved review comments.
Awaiting CMC stability data lock
Milestone Dependency Strip
Protocol finalization
Statistical analysis plan lock
Module 5 compilation
Dispatch submission
| Milestone | Due Date | Owner | Dependencies | Dependency Indicators | Completed |
|---|---|---|---|---|---|
| Protocol finalization | 2025-01-23 | Lieselotte van der Berg | None | Independent | No |
| Statistical analysis plan lock | 2025-03-02 | Sarah Chen | None | Independent | No |
| Module 5 compilation | 2025-04-01 | Nadia Petrova | PLAN-053-MS-002 | Dependent | Yes |
| Dispatch submission | 2025-04-18 | Marcus Webb | PLAN-053-MS-003 | Dependent | No |